Energized by some of the greatest tides in the world, this area includes the expansive delta of the once mighty Colorado River and numerous wetlands and estuaries, which serve as nursery grounds for marine species and resting places for resident and migratory birds. The area is known for its many endemic species, as well as commercially important populations of shrimp, blue crabs and clams. It is home to four highly endangered species including the endemic Gulf of California harbor porpoise or vaquita and the totoaba. Reduced freshwater, declining nutrient flow and diminished water quality along with poorly-managed, non-selective fishing practices are the greatest perils to this once-rich ecosystem.

The northern Gulf of California is an area of extreme temperatures, salinity, and tides (23 ft. maximum). Many unique organisms have adapted to these conditions, some with seasonal cycles of abundance.

On the edge of the Upper Gulf of California and Colorado River Delta Biosphere Reserve, rocky intertidal habitats (with beach rock, granite and basalt substrates) and sandy beaches dominate the landscape surrounding Puerto Peñasco. Several negative estuaries (esteros) are located on the outskirts of town. Thirty miles north of CEDO lies the Pinacate Biosphere Reserve.

All of these habitats are readily accessible from the CEDO facility.

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